NFL: San Francisco 49ers vs New York Giants
San Francisco 49ers vs New York Giants Spread: 49ers -2.5 (-109) WINNER Giants +2.5 (-105) Total: Over 48.5 (-108) WINNER Under 48.5 (-108) Moneyline: 49ers
November 2, 2025
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San Francisco 49ers vs New York Giants Spread: 49ers -2.5 (-109) WINNER Giants +2.5 (-105) Total: Over 48.5 (-108) WINNER Under 48.5 (-108) Moneyline: 49ers
San Francisco 49ers vs Houston Texans Spread: 49ers +3 (-122) Texans -3 (+106) WINNER Total: Over 42 (-108) Under 42 (-108) WINNER Moneyline: 49ers (+128)
Atlanta Falcons vs San Francisco 49ers Spread: Falcons -1.5 (-102) 49ers +1.5 (-120) WINNER Total: Over 46.5 (-105) Under 46.5 (-115) WINNER Moneyline: Falcons (-108)
San Francisco 49ers vs Tampa Bay Bucs Spread: 49ers +3.5 (-118) Bucs -3.5 (-104) WINNER Total: Over 46.5 (-118) WINNER Under 46.5 (-104) Moneyline: 49ers
NFC West Remains Tight… Both teams enter Thursday Night’s matchup at 3-1 on the young season. However, the 49ers currently sit 2-0 in NFC West
Jacksonville Jags vs San Francisco 49ers Spread: Jags +3 (-113) WINNER 49ers -3 (-105) Total: Over 45.5 (-108) WINNER Under 45.5 (-113) Moneyline: Jags (+140)
NFL: Arizona Cardinals vs San Francisco 49ers Spread: Cardinals +1.5 (-110) WINNER 49ers -1.5 (-110) Total: Over 44.5 (-110) Under 44.5 (-110) WINNER Moneyline: Cardinals
NFL Week Two: San Francisco 49ers vs New Orleans Saints Spread: 49ers -3 (-104) WINNER Saints +3 (-118) Total: Over 40.5 (-110) WINNER Under 40.5
San Francisco 49ers vs Seattle Seahawks Spread: 49ers -1.5 (-120) WINNER Seahawks +1.5 (-102) Total: Over 43.5 (-104) Under 43.5 (-118) WINNER Moneyline: 49ers (-125)
NFL Preseason: San Francisco 49ers vs Las Vegas Raiders Spread: 49ers +4.5 (-120) Raiders -4.5 (-102) Total: Over 41.5 (-110) Under 41.5 (-110) Moneyline: 49ers
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